4 ms·
the drug's ability to slow down cognitive decline was small but statistically significant and dose dependent. It is a huge deal. It is also interesting that t
by hcknwscommenter 8y ago
the drug's ability to slow down cognitive decline was small but statistically significant and dose dependent. It is a huge deal. It is also interesting that the drug selectively targets protofibrils. This is interesting because A/Beta peptide is difficult to target because there is so much of it. Fibrils are difficult to target because they are insoluble. Selectively targeting protofibrils means the drug binds an accessible target and will not be titrated out by A/Beta peptide.