Yes they accept that large trials are obviously needed. > The results suggest that memory loss may be reversed and improvement sustained with the therapeutic p

Yes they accept that large trials are obviously needed. > The results suggest that memory loss may be reversed and improvement sustained with the therapeutic program, but Bredesen cautioned that the results need to be replicated. > “The current, anecdotal results require a larger trial, not only to confirm or refute the results reported here, but also to address key questions raised, such as the degree of improvement that can be achieved routinely, how late in the course of cognitive decline reversal can be effected, whether such an approach may be effective in patients with familial Alzheimer’s disease, and last, how long improvement can be sustained,” he said. From http://newsroom.ucla.edu/releases/memory-loss-associated-with-alzheimers-reversed-for-first-time http://newsroom.ucla.edu/releases/memory-loss-associated-wit...