4 ms·
In what sense is this a "discovery"? Observational studies of this type cannot show causality, and the results have not been confirmed by independent methods.
by oldgradstudent 8y ago
In what sense is this a "discovery"?
Observational studies of this type cannot show causality, and the results have not been confirmed by independent methods.
- gwern 8y ago> Observational studies of this type cannot show causality They can: sibling comparisons. > the results have not been confirmed by independent methods. They're tested out of sample many times (4 for sibling comparisons alone!), and you can find many other papers successfully using the IQ GWASes. Belsky et al 2018 just came out a few weeks ago, for a particularly good example testing OP's PGS. (The PGS has been out since like March, so several papers have used it.)
- oldgradstudent 8y ago>> Observational studies of this type cannot show causality >They can: sibling comparisons. But then they get much lower concordance so they come up with various ad-hoc hypotheses to explain it, instead of acknowledging the negative result. This is an hypothesis generating paper, using a highly suspect methods. Not a discovery.