3 ms·
It would be remarkable if there was not some predictive value when applied to AA datasets given the level of European ancestory in the AA population is around 3
by danieltillett 8y ago
It would be remarkable if there was not some predictive value when applied to AA datasets given the level of European ancestory in the AA population is around 30%.
- gwern 8y ago(Closer to 20%, and the attenuation of 85% is about what you would expect; we already know that that's the usual level of decrease when you test PGSes in AAs, and it goes to near-zero in African populations. It looks like it's not an issue of entirely different causal variants or different environments, but mostly LD tagging decay.)
- danieltillett 8y agoThe estimated range is 16.7% to 29% according to the fount of all wisdom wikipedia [0]. 0. https://en.wikipedia.org/wiki/African_Americans https://en.wikipedia.org/wiki/African_Americans
- millermp12 8y agoIt would be remarkable that someone would fall on their sword like that today. It'll be another couple of years before "The Flippening", i.e. scientists looking to cement their legacy doing the political calculation and deciding they'd rather risk some short term fallout vs joining Lyskenko and Lamarck in the history book. That elaborate kabuki we saw from David Reich at Harvard a few months ago? It'll get even more entertaining in the coming months and years as that fig leaf continues to shrink.