4 ms·
Anecdotally I’ve consumed 50-75 100mcg doses of 1P-LSD over the last year and found it almost indistinguishable from LSD. Not to mention easier and safer to obt
by throwaaaay 8y ago
Anecdotally I’ve consumed 50-75 100mcg doses of 1P-LSD over the last year and found it almost indistinguishable from LSD. Not to mention easier and safer to obtain (directly from a research lab).
Obviously there is no research on long term effects at this point, and there may never be, but for my personal therapeutic rituals it’s affectiveness is the same.
It’s also worth noting that I’m not microdosing, which you may have assumed from my doses over time. I’m taking it once a week at an average dose of 300-600mcg with a 1-2 week break every 4 weeks (obviously I didn’t start at this dose when I first tried it). Along with other health supplements and exercise just so were clear.
I am an experienced psychonaut, but I’m not a doctor, and I’m not here to champion 1P-LSD nor my personal rituals. But this is my experience.
- Aspyre 8y agoCool! Glad to see mention of 1P here. I'm a fan of it myself.
- tibbon 8y agoIsn't 1P-LSD the ones that metabolizes into LSD-25?
- throwaaaay 8y agoAFAIK it has not been proven if it breaks down into lsd-25 of if 1p itself fits into the 5-ht receptor as it’s own in vivo. >It has been theorized that 1P-LSD may act as a prodrug for LSD. While 1P-LSD shows only 38% the potency of LSD in mice, LSD is detected via LC-MS when 1P-LSD is incubated in human serum. Follow-up studies are currently being conducted to compare the affinity and selectivity of LSD and 1P-LSD at 5-HT receptors, and to determine whether 1P-LSD is hydrolyzed to LSD in vivo.[1] Otherwise, it is possible that 1P-LSD may be capable of exerting its own psychedelic effect. https://psychonautwiki.org/wiki/1P-LSD https://psychonautwiki.org/wiki/1P-LSD