As someone on a phase 2 trial an interesting note is that I know I'm on the trial drug (it's not a double blind trial), I also know that the drug worked in anim

As someone on a phase 2 trial an interesting note is that I know I'm on the trial drug (it's not a double blind trial), I also know that the drug worked in animal and vitro trials. Furthermore I know, from the trial literature, that a very similar drug works (the trial drug is an anti-PD-1 immunotherapy) well with the particular genetic markers on my tumours. The trial is to assess the efficacy of this treatment, not run a comparison to other treatments, but having burnt through 2 rounds of chemo in short order to no effect it is more a comparison against that. Whether the placebo effect is relevant is an interesting question because under the trial the treatment is, by necessity, more personalised. Previous studies have shown that, essentially, human contact/interest adds to the placebo effect.