3 ms·
I'm not aware of any phage treatments suitable for lung infections - mostly, it's been skin and soft tissue sites, but I'd be happy to know if there is one. An
by Fomite 8y ago
I'm not aware of any phage treatments suitable for lung infections - mostly, it's been skin and soft tissue sites, but I'd be happy to know if there is one.
And yes, highly resistant infections are a problem - and one I work on - but from a "market forces" perspective they're still relatively rare. Even for most highly resistant infections we still have some antibiotics that work - not well, and not without side effects, etc.
- azernik 8y agoNot any current standard phage mixtures, but especially for lung disease they're an active area of research. Delivery mechanisms seem to be a pretty solved/relatively-trivial problem. See e.g. https://www.sciencedirect.com/science/article/pii/S1569199317308147 https://www.sciencedirect.com/science/article/pii/S156919931... In this particular case, they found a phage for the particular infection, but at too late of a stage - most of the development I've heard of has been less about basic research and more about building institutional processes for quickly finding existing predators of a given bacterium. (Which, I agree, is a lot more expensive and risky than an antibiotic if you can find one that works.)
- Fomite 8y agoYeah - I think the biggest hurdle is actually "...how do we do this?" at the site of treatment (both biological and clinical). I'm very sorry for your loss.