3 ms·
Alzheimer's actually gets a lot of funding, but mostly for therapeutics, not diagnostics: it gets a lot of funding from NIH, and neurodegenerative disease trea
by aaavl2821 8y ago
Alzheimer's actually gets a lot of funding, but mostly for therapeutics, not diagnostics: it gets a lot of funding from NIH, and neurodegenerative disease treatments get the third or fourth most VC and big pharma funding (after cancer, rare disease and maybe infectious disease)
However none of the drugs really work, and ppl think one reason is bc patients are diagnosed too late
Diagnostics get very little funding in general, not just in Alzheimer's. Calling yourself a "diagnostics" company is a good way to get ignored by VCs. You have to do a lot of expensive studies to prove that they work, the bar is quite high to getting insurers to pay for them, and pricing power is low. Most insurers will only pay for a novel diagnostic if it saves them money. So you have high development cost and low profit potential
- CamelCaseName 8y ago>Calling yourself a "diagnostics" company is a good way to get ignored by VCs. [...] So you have high development cost and low profit potential What can regulatory agencies do to alleviate this?
- aaavl2821 8y agoThe regulation for many diagnostics is actually fairly light. There's a class of diagnostics called "lab developed tests" that essentially aren't regulated by FDA The development cost is high because you need good data to convince doctors that tests work, and also to convince payers. Payers have proven to be the real gatekeepers for many diagnostics rather than FDA