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It is number two in the world by total number of flights per year: http://www.traveller.com.au/worlds-busiest-airline-flight-routes-melbournesydney-now-worlds-s

• Reason077 8y ago
  Indeed. That’s because Qantas and their competitors use a large number of small aircraft on the route, maintaining a high frequency. If you look at the real busiest routes (by passenger count), like Singapore to KL, they tend to use larger wide body aircraft which carry a lot more passengers per flight.