If I were in your shoes, I would start with vanilla ES 5 (no package manager or framework) and build a simple project. In the beginning, you want to figure out

If I were in your shoes, I would start with vanilla ES 5 (no package manager or framework) and build a simple project. In the beginning, you want to figure out big concepts like the event loop and all the ansynchronous stuff. When you first get started, all sorts of shit is going to be undefined, so log everything to the console and pay attention to how variables go from undefined to defined. If you can't think of an idea, try building an accurate HIIT timer with vanilla JavaScript. Have a simple backend where you can save/retrieve/edit results and build an interface for that. But, don't get bogged down in package management, Webpack, libraries or any of the other shit. Once you're finished that, ideally, you'll be in a position where you feel in control of your variables. You'll have some understanding of how JavaScript chains together, and a sense of how things will happen under the hood. Hopefully, you'll also be good with your chosen browser and its developer tools, especially the JavaScript console. And, with some luck, you'll have enough exposure to the 'interesting' parts of JavaScript that moving to ES 6 will seem like an actual upgrade. At that point, you should be ready to start learning slightly more modern JavaScript. Then, it would be wise to move into a framework. Currently, your three big choices are Vue, React and Angular. I have little experience with Vue, so I'll let more experienced people weigh in there. Angular seems to be getting a little less popular, though it could just be because, since they started using semver, they've seemingly released a new version every eleven minutes.