5 ms·

So some sort of critical mass was hit after x years and if that bet was wrong they are doomed for the next 20-40? Why didn't they wait until an actual definitiv

• db48x 8y ago
  Nobody understand the brain well enough to do that yet. Furthermore, the existence of a cure for a disease goes a long way towards proving what the mechanism of the disease is.
  • nonbel 8y ago
    >"Nobody understand the brain well enough to do that yet." I'm fairly certain I understand the brain well enough to know our understanding of the brain is rudimentary and there is no reason to become attached to a vague preliminary model like this "amyloid hypothesis".
    • db48x 8y ago
      It's not so vague as it might sound. There's good evidence that people with amyloid plaque build-up, in the brain or in other organs, have different versions of the genes that code for the production of amyloid proteins than people who do not.