That certainly makes sense with THC, and ties back to your earlier remark about clinically significant quantities of it. For some studies, I've seen reference

That certainly makes sense with THC, and ties back to your earlier remark about clinically significant quantities of it. For some studies, I've seen reference to using an active placebo (so the placebo group feels something), but I realize that can pollute the side effects data, and it may be useless for psychoactives where the effect is publically well-known.