I use them together, uMatrix as a fine grained control tool where I can setup a saved profile and click-allow until functionality & appearance are acceptable to

I use them together, uMatrix as a fine grained control tool where I can setup a saved profile and click-allow until functionality & appearance are acceptable to me, and for 'one-off' or 'fuck-it no time' situations I just toggle uMatrix off. It is very rare I have to turn off uBlock Origin as well (the nuclear option). This leaves me four-five quick clicks away from the median or average user experience.