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Re: 1: It wasn’t wrong. There are Mendelian traits and complex traits. We shouldn’t forget we’ve basically tracked down most Mendelian diseases since the human
by skosuri 8y ago
Re: 1: It wasn’t wrong. There are Mendelian traits and complex traits. We shouldn’t forget we’ve basically tracked down most Mendelian diseases since the human genome was published. Still some to go but we will hopefully have all soon. This is a huge accomplishment.
Complex/quantitative traits on the other hand have been known for quite some time. I don’t think it’s anything new, but the landscape is becoming increasingly clear thanks to large scale GWAS and analyses from many groups including Pritchard’s.