3 ms·

I, personally, don't consider Vioxx a failing of the FDA. I might be wrong, but reading the Wikipedia article makes it sound like more of issues surrounding the

by lykr0n 8y ago

I, personally, don't consider Vioxx a failing of the FDA. I might be wrong, but reading the Wikipedia article makes it sound like more of issues surrounding the drug's promotion and marketing- not the drug itself (considering the US and Canada both voted to allow it back on the market). And OxyContin's issues (I think) fall on the DEA and not the FDA. Oxy does what it is supposed to do really well, and the side affects are known. I just used Thalidomide as an example of where the FDA got it right. The fact that we havn't see other drugs like that pop up, tells me that the system is working.

beagle3 8y ago
> I, personally, don't consider Vioxx a failing of the FDA. I was following the case in real time, and it certainly looked like a failing of the FDA and being way way too cozy with Merck about it; compared to how it looked then, the wikipedia article looks incredibly white washed. I'm not sure we read the same Wikipedia article - the one I read said that Merck withheld information from the FDA, and makes no mention of any resulting sanctions or penalties (which is exactly how I remember it). Does this sound like a working regulatory agency to you? > And OxyContin's issues (I think) fall on the DEA and not the FDA. Oxy does what it is supposed to do really well, and the side affects are known. Not at all. Perdue made false claims about how long acting OxyContin is, and as a result of the recommended prescription, many people both suffered and got hooked, see e.g. [0], which was the first result for "oxycontin perdue abuse", but by no means the only one. > I just used Thalidomide as an example of where the FDA got it right. The fact that we havn't see other drugs like that pop up, tells me that the system is working. ... to me, the fact that Thalidomide is basically the only example that everyone brings up, it means that the European system is essentially equally effective, despite your implied claim ("Europe had a massive problem, while the US didn't.") that the US one is superior. [0] https://www.nytimes.com/2018/05/29/health/purdue-opioids-oxycontin.html https://www.nytimes.com/2018/05/29/health/purdue-opioids-oxy...

by lykr0n 8y ago

beagle3 8y ago

> I, personally, don't consider Vioxx a failing of the FDA. I was following the case in real time, and it certainly looked like a failing of the FDA and being way way too cozy with Merck about it; compared to how it looked then, the wikipedia article looks incredibly white washed. I'm not sure we read the same Wikipedia article - the one I read said that Merck withheld information from the FDA, and makes no mention of any resulting sanctions or penalties (which is exactly how I remember it). Does this sound like a working regulatory agency to you? > And OxyContin's issues (I think) fall on the DEA and not the FDA. Oxy does what it is supposed to do really well, and the side affects are known. Not at all. Perdue made false claims about how long acting OxyContin is, and as a result of the recommended prescription, many people both suffered and got hooked, see e.g. [0], which was the first result for "oxycontin perdue abuse", but by no means the only one. > I just used Thalidomide as an example of where the FDA got it right. The fact that we havn't see other drugs like that pop up, tells me that the system is working. ... to me, the fact that Thalidomide is basically the only example that everyone brings up, it means that the European system is essentially equally effective, despite your implied claim ("Europe had a massive problem, while the US didn't.") that the US one is superior. [0] https://www.nytimes.com/2018/05/29/health/purdue-opioids-oxycontin.html https://www.nytimes.com/2018/05/29/health/purdue-opioids-oxy...