Although standard awk has the advantage of being installed on all POSIX systems, for bioinformatics there's a nifty bioawk (https://github.com/lh3/bioawk https:

Although standard awk has the advantage of being installed on all POSIX systems, for bioinformatics there's a nifty bioawk (https://github.com/lh3/bioawk https://github.com/lh3/bioawk) that extends awk so that records aren't necessarily lines but fasta/fastq records as well. Pretty neat for oneliners.