TLDR: "Moore concluded that a 200 year-long mission should have an initial crew of 150 – 180 people. (...) Among other results, it was found that an initial cre

TLDR: "Moore concluded that a 200 year-long mission should have an initial crew of 150 – 180 people. (...) Among other results, it was found that an initial crew of 14000 – 44000 members is well-optimized to ensure healthy offspring, even in the case of a sudden disaster occurring once during the mission. According to his study, a crew of 150 people would always be on the verge of extinction in the case of a large-scale catastrophe." https://arxiv.org/ftp/arxiv/papers/1708/1708.08649.pdf https://arxiv.org/ftp/arxiv/papers/1708/1708.08649.pdf I had to go to the linked study to get the answer. If an article posits a question in the title...it should answer it in the body. Hopefully in the first paragraph.