An under-emphasized detail is what your college's policy is on leave-of-absences, or allowing dropouts to return. For me, dropping out to try my first startup

An under-emphasized detail is what your college's policy is on leave-of-absences, or allowing dropouts to return. For me, dropping out to try my first startup and returning to school after it failed was literally filling out a single-sided form when I left and filling out a similar single-sided form when I wanted to return. If it's that easy at your college, the risk of dropping out is extremely small, so if you have an idea you are passionate about and the opportunity to execute on it, you may as well try. I'll bet somebody told Mark Zuckerberg that he was probably not Bill Gates, so he should probably stay in school.