Irresponsible implies a moral imperative. I think they're saying that "unintended consequences" often harm other people, and therefore business have the respons

Irresponsible implies a moral imperative. I think they're saying that "unintended consequences" often harm other people, and therefore business have the responsibility to minimize them. The stereotype is that American business like Uber, Facebook, and Amazon tend to see shareholder value as their one and only duty.