I don't know if this will be on-topic for you, but: I'll speculate that chronic self-criticism is, results from, and/or produces chronic stress. Chronic stress

I don't know if this will be on-topic for you, but: I'll speculate that chronic self-criticism is, results from, and/or produces chronic stress. Chronic stress is known to be harmful to health in several ways. You might start with an interesting article [1]: From Stress to Inflammation and Major Depressive Disorder: A Social Signal Transduction Theory of Depression. Not paywalled, maybe a place to begin looking at connections between self-criticism (which I find immensely stressful and debilitating) and consequent illnesses. [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006295/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006295/