Another thing that comes to mind is that using current devices (such as two 22" displays, i.e., a much higher resolution like 3360x1050), the time to do anythin

Another thing that comes to mind is that using current devices (such as two 22" displays, i.e., a much higher resolution like 3360x1050), the time to do anything meaningful with a pointing-device increases, too. I, for instance, switched to a big trackball device because all this mouse lifting and re-centering became annoying. As for the simple tasks: Something like Emacs macros enable effective processing of raw text input data--something that would take a lot longer if it had to be done manually, if possible at all.