4 ms·

Salt is one of the bodies most hormonally regulated substances after maybe glucose. The electrolytes Na and Cl are routinely and easily measured on basic blood

Salt is one of the bodies most hormonally regulated substances after maybe glucose. The electrolytes Na and Cl are routinely and easily measured on basic blood chemistry panels. My patients with migraines don't have low salt. cant say I'm a migraine researcher or know what causes migraines but this doesn't seem like a reasonable hypothesis.

kuwze 8y ago
Hey man I am way out of my depth here, but the study really speaks for itself: > Our analysis population was 8819 adults in the 1999–2004 National Health and Nutrition Examination Survey (NHANES) with reliable data on diet and headache history. Compare that to Aimovig: > The 12-week trial, presented this week at the annual meeting of the American Academy of Neurology, involved 246 patients suffering four to 14 migraine headaches a month who had tried two to four preventive treatments that either did not work for them or had intolerable side effects. [0] [0]: https://www.reuters.com/article/us-amgen-migraines-aimovig/amgens-aimovig-halved-migraine-days-in-30-percent-of-trial-patients-idUSKBN1HO348 https://www.reuters.com/article/us-amgen-migraines-aimovig/a...
- aodin 8y ago
  You're comparing a survey (NHANES), which is a questionnaire completed by volunteers, to an active treatment medical study with a placebo control group. Comparing the N count between these two is essentially apples to oranges. As to the results of the salt intake survey (Pogoda et al.), it is describing a correlation, not a causation. The actual relationship between salt intake and migraines could also be inverted, or completely independent.
  - ianai 8y ago
    It’s easy enough to rule out. When I have a migraine and haven’t had Gatorade in a while, I’ll guzzle some down (preferably cold enough for a cold headache). It’s definitey not affecting the large majority of my migraines, but I at least know I tried that avenue too.
    - jjeaff 8y ago
      Sounds like you might be dehydrated, which is definitely a known trigger for severe headaches.
  - kuwze 8y ago
    You’re right. I am unfamiliar with the research; shouldn’t have posted that snarky reply.

kuwze 8y ago

Hey man I am way out of my depth here, but the study really speaks for itself: > Our analysis population was 8819 adults in the 1999–2004 National Health and Nutrition Examination Survey (NHANES) with reliable data on diet and headache history. Compare that to Aimovig: > The 12-week trial, presented this week at the annual meeting of the American Academy of Neurology, involved 246 patients suffering four to 14 migraine headaches a month who had tried two to four preventive treatments that either did not work for them or had intolerable side effects. [0] [0]: https://www.reuters.com/article/us-amgen-migraines-aimovig/amgens-aimovig-halved-migraine-days-in-30-percent-of-trial-patients-idUSKBN1HO348 https://www.reuters.com/article/us-amgen-migraines-aimovig/a...

aodin 8y ago
You're comparing a survey (NHANES), which is a questionnaire completed by volunteers, to an active treatment medical study with a placebo control group. Comparing the N count between these two is essentially apples to oranges. As to the results of the salt intake survey (Pogoda et al.), it is describing a correlation, not a causation. The actual relationship between salt intake and migraines could also be inverted, or completely independent.
- ianai 8y ago
  It’s easy enough to rule out. When I have a migraine and haven’t had Gatorade in a while, I’ll guzzle some down (preferably cold enough for a cold headache). It’s definitey not affecting the large majority of my migraines, but I at least know I tried that avenue too.
  - jjeaff 8y ago
    Sounds like you might be dehydrated, which is definitely a known trigger for severe headaches.
- kuwze 8y ago
  You’re right. I am unfamiliar with the research; shouldn’t have posted that snarky reply.