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The scientist and I don't disagree; I think we just have a semantic difference. If the cancer is genetically different from the expectation, then it requires a
by carbocation 16y ago
The scientist and I don't disagree; I think we just have a semantic difference. If the cancer is genetically different from the expectation, then it requires a different treatment. So if you have a disease that looks just like CML but doesn't have a Bcr/Abl fusion tyrosine kinase, imatinib is probably not what we'd want to use. I would call that molecule-centric, and s/he might call it patient-centric. Either way, the wording doesn't matter so long as you're treating the patient with the most appropriate therapy.
- bitdiddle 16y agoI see, well I'll certainly take your word for it. I really need to read more of this literature as I've been working with these folks quite a bit, and hardly know the difference between a gene and a protein.
- carbocation 16y agoAre you doing bioinformatics? If so, it's a great excuse to learn more about the field, and learning more about the field will make you care more about the work you're doing--a feed-forward loop. At least, when I started doing medical genetic research, that's how things worked for me.
- bitdiddle 16y agosort of, I work in description logics, they are used to build medical terminologies. NCI has used them over the years in cancer genomics. A good amount has rubbed off just hanging out with these folks but recently I've become keen to learn more.