Can't you use a designer GUI to develop the static GUIs? You will have to understand how layouts actually work and how the designer translates your design into

Can't you use a designer GUI to develop the static GUIs? You will have to understand how layouts actually work and how the designer translates your design into code/widgets/layouts. Then in Python you write your logic and event handlers. Qt also offers QML, if you are a fan of how those components look you may enjoy using it.