Affects directly or indirectly. But indeed, anything that does not affect anything that affects anything [..] that could be perceived, can not be considered in

Affects directly or indirectly. But indeed, anything that does not affect anything that affects anything [..] that could be perceived, can not be considered in any meaningful way to belong to our universe. Isn't that the meaning of "universe"? The set of all things closed under all possible physical interactions?