4 ms·
> You also expect the number of identified cases to increase as we improve detection methods and find tumors earlier. If this is true (and I think you're likel
by carbocation 8y ago
> You also expect the number of identified cases to increase as we improve detection methods and find tumors earlier.
If this is true (and I think you're likely to be right) then we should see longer survival with GBM thanks to lead-time bias.
- awakeasleep 8y agoIt's actually more complicated than that- we'd need to know the survival rate for procedures carried out at different discovery times. If the cancer is basically inoperable, or if there isn't a big difference in outcome based on time of detection, then there wouldn't be an appreciable change in survival rates
- carbocation 8y ago> If the cancer is basically inoperable, or if there isn't a big difference in outcome based on time of detection, then there wouldn't be an appreciable change in survival rates Lead time bias tells you that even if there is no effective treatment, you will appear to live longer thanks to earlier discovery of the disease. It was a hot topic with regard to prostate cancer a few years ago.