3 ms·
I dont think this motif brings anything spooky/special to the fore. DNA is swarmed by proteins, ribocomplexes, acetyl/methyl histone mods, etc. all of its own m
by subroutine 9y ago
I dont think this motif brings anything spooky/special to the fore. DNA is swarmed by proteins, ribocomplexes, acetyl/methyl histone mods, etc. all of its own making. Whatever special computation one might speculate this motif could perform- that computation or fidelity check or whatever else is probably a known and well-documented function of some DNA-associating complex. While it's fun to speculate how this might 'change the game', in all likelihood, this finding is a very small drop in a very large bucket.
But if we are speculating...
That a motif forms by a single strand of DNA or RNA is expected (given certain properties or symmetries). What the image in the article depicts and given the quote that this is often seen at start codons, to me, suggests this motif forms whenever transcription machinery has opened the helix creating two single strands. And instead of hanging out as single strands (a very vulnerable state, to DNase degradation, etc) they coil unto themselves. This might also suggest this segment of DNA is relatively easy to unzip, and has built-in degredation protection, making for ideal consensus sequences as start codons.