A read operation determines if the connection is "connected" or "disconnected". It actually is litte bits of wire inside silicon that get over-current'ed and d

A read operation determines if the connection is "connected" or "disconnected". It actually is litte bits of wire inside silicon that get over-current'ed and do burn away. And then a read operation returns "Disconnected". There's no way to 'reconnect' a eFuse, in the way there's no way to reconnect an automotive fuse. So yes, eFuses are a form of hardware destruction.