4 ms·

Exercise. Certainly not as sexy as Ketamine. But it's effective. There's lots of studies... here's one pulled out of the bag: https://www.ncbi.nlm.nih.gov/pmc/

• sonthonax 9y ago
  I think a lot of the first line remedies for depression (such as exercise, increase social contact, sleep better, etc) highlights the issue with empirical methodologies used to describe experience. Correlation really becomes causation at a certain point. People who sleep well, have strong social lives, and exercise frequently are rarely depressed. This isn't because of some biochemical reaction, but simply doing the above doesn't fit the definition of depression.
• mcjiggerlog 9y ago
  I've tried pretty much everything for fighting depression - drugs, meditation, the lot. The only thing that consistently works is running nearly every day. I assume any intense cardio will do, though something outside is obviously better.
• peterbraden 9y ago
  The problem with relying on exercise as a coping mechanism is that you may get injured and therefore will have no fallback.