I don't think this is ignored by the scientific community at all. For example, Eric Lander's group has a pretty nice treatment of why additive models can't expl

I don't think this is ignored by the scientific community at all. For example, Eric Lander's group has a pretty nice treatment of why additive models can't explain heritability [1]. And this is coming from the same Eric Lander who has done some of the key work in complex disease / additive genetic modeling. Imagine you're in a world where you are handed down some knowledge there are Newtonian models, and more advanced models that use relativity, but you don't know what the constants are yet. We're still looking for the Newtonian constants. We know there is much more out there once we understand the basics. But the basics are still worth understanding. 1 = http://www.pnas.org/content/109/4/1193 http://www.pnas.org/content/109/4/1193