Weird that my first guess isn't considered, that it could be from a now extinct plant, perhaps harvested to extinction like the abortifacient plant used in anci

Weird that my first guess isn't considered, that it could be from a now extinct plant, perhaps harvested to extinction like the abortifacient plant used in ancient Rome or destroyed in after the plant drew the ire of someone powerful. Or maybe the plant is still out there. Unlikely to be related, but possibly, Tramadol was thought to be naturally produced by a root in Cameroon but then found to be in high levels in the soil, water, and other plants because people and their animals were consuming high quantities.