I'm not sure if this is the same thing you are suggesting, but what I like to do is use the "Manage people" option from the menu at the top right. My work and h

I'm not sure if this is the same thing you are suggesting, but what I like to do is use the "Manage people" option from the menu at the top right. My work and home google accounts are never logged in at the same time in the same chrome window. It seems to keep everything separated pretty well, even extensions seem to maintain their own settings/"activated-ness" within each person/account.