3 ms·
True, but what did doctors do before these new drugs? “Fuck around” with “inferior” products... reason I’m cynical is because many new drugs that hit the market
by cko 9y ago
True, but what did doctors do before these new drugs? “Fuck around” with “inferior” products... reason I’m cynical is because many new drugs that hit the market are not novel - for example loteprednol (older drug) vs difluprednate (newer): https://www.ncbi.nlm.nih.gov/m/pubmed/28628490/ https://www.ncbi.nlm.nih.gov/m/pubmed/28628490/
By the way, some of these newer drugs don’t have to be “superior” to be approved, they just have to be none-inferior to current therapy.
https://www.raps.org/regulatory-focus™/news-articles/2016/11/when-can-non-inferiority-trials-establish-efficacy-fda-explains-with-guidance https://www.raps.org/regulatory-focus™/news-articles/2016/11...
- darpa_escapee 9y agoFrom what I gathered, it was more effective than the cheaper options, not that it was chosen because it was new and shiny.