I have used MediaWiki for unstructured information with additional extensions for structured data (Semantic MediaWiki or Cargo) with Page Forms Extension. This

I have used MediaWiki for unstructured information with additional extensions for structured data (Semantic MediaWiki or Cargo) with Page Forms Extension. This is difficult and time-consuming to setup. But if you cann afford the effort, this gives you a very flexible system where you can decide what to store in a structured or unstructured manner. Structured data can of course be queried, aggregated, vizualized etc. Together with the Page Forms extension this can replace many Excel Spreadsheets and MS Access solutions. If you really know what you're doing, you can even do moderately complex CRUD Applications. But then you really need to know your way around several extensions and of course wikitext. For simpler use-cases I've also used Drupal. For this use case it's not as flexible as MediaWiki, but you can do a lot through the GUI and build custom Forms / Views.