I'm shamelessly pulling all of this from the paper abstract, which you should find here: https://www.nature.com/articles/s41591-018-0004-z https://www.nature.co

I'm shamelessly pulling all of this from the paper abstract, which you should find here: https://www.nature.com/articles/s41591-018-0004-z https://www.nature.com/articles/s41591-018-0004-z As for what this means: it's exciting, and if these researchers can prove that the drug is safe in animals and humans they can probably proceed with trials on Alzheimer's patients with the apoe4 gene. But that's the thing: this discovery, while cool, is relevant to only some of the patients dealing with Alzheimer's that have the ApoE4 gene. This isn't a unifying mechanism to how Alzheimer's occurs in all patients, as it doesn't tackle the problem of patients with apoe3 getting Alzheimer's. Nonetheless it is still relevant especially for early onset, which is more strongly associated with this gene.