You could start with mithril.js, it's a react-like vdom library with a minimal set of api, and vanilla JS for everything else. I've been using it the past 6 we

You could start with mithril.js, it's a react-like vdom library with a minimal set of api, and vanilla JS for everything else. I've been using it the past 6 weeks and super happy with it. I'm sticking with the hyperscript form of it, but you can use JSX if you want.