2 ms·
The obvious question which isn't addressed in the article - do beta-amyloid levels return to normal after some short span of good sleep? Alzheimer's is associa
by Bartweiss 9y ago
The obvious question which isn't addressed in the article - do beta-amyloid levels return to normal after some short span of good sleep?
Alzheimer's is associated with consistently elevated beta-amyloid levels, while this study was about a short-term increase. It appears on a skim of the study that the rate wasn't checked over later days, but is expected (from rodent models) to go back down reasonably quickly. That's not a criticism of the study - it's an interesting result linking the disrupted sleep patterns seen in pre-Alzheimers to the protein levels seen in Alzheimer's, and it's also the first study to directly study this link in humans.
It just seems like an important caveat because the New Scientist article is a bit fuzzy on whether individual bad sleep events are being seen as a model (yes) or a risk factor (not so far) for Alzheimer's.