The study investigates three non-caloric artificial sweeteners: saccharin, sucralose, and aspartame. "To determine the effects of NAS on glucose homeostasis, w

The study investigates three non-caloric artificial sweeteners: saccharin, sucralose, and aspartame. "To determine the effects of NAS on glucose homeostasis, we addedcommercial formulations of saccharin, sucralose or aspartame to the drinking water of lean 10-week-old C57Bl/6 mice" "Notably, at week 11, the three mouse groups that consumed water, glucose and sucrose featured comparable glucose tolerance curves, whereas all three NAS-consuming mousegroups developed marked glucose intolerance (P , 0.001, Fig. 1a, b)." The article probably only talks about saccharin specifically because, as the study states: "...saccharin exerted the most pronounced effect, [so] we further studied its role as a prototype artificial sweetener."