3 ms·
As far as I've heard 10,000 IU is regarded as almost definitely non-toxic, and toxicity seems to have been noticed around 40,000 IU per day. However, in the su
by mtgx 9y ago
As far as I've heard 10,000 IU is regarded as almost definitely non-toxic, and toxicity seems to have been noticed around 40,000 IU per day.
However, in the summer you may want to drop that below 5,000 or even stop supplementing completely, depending how much you're in the sun.
Vitamin K2 also seems to be necessary in combination with D3. But it's not clear to me if 100 mcg MK-7 is enough or if you need to supplement Mk-4 more often or eat more MK-4 foods (the latter is probably preferable).
- logfromblammo 9y agoThe largest-dose individual, non-prescription vitamin D supplement pill I have ever seen is 5000 IU, so you'd have to take 10 of those every day, for months, to develop a toxicity symptom. At that point, the per-pill cost of the supplement and the sheer number of pills combine to discourage overdose. If you have a confirmed deficiency, a doctor can prescribe a limited course of higher-dose pills to get your serum levels back up quickly. I take cholecalciferol (D3) and menatetrenone (K2-MK4) daily, along with a multivitamin that was essentially a gratis 2.7-year supply, thanks to a fortuitous coupon + sale price interaction, so it isn't actually just making my pee more expensive. I'd feel wasteful throwing it away after someone paid me to take it home, and it'd be great if it activated a placebo effect. Also, I can't bring myself to like natto.