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This is a critical comment that should be upvoted widely. The reason that this is such a difficult challenge is that the rate of adult hippocampal neurogenesis,
by ckemere 9y ago
This is a critical comment that should be upvoted widely. The reason that this is such a difficult challenge is that the rate of adult hippocampal neurogenesis, even in rodents where everyone believes it happens, is on the order of between 1 neuron per minute and 1 neuron per hour. In a brain of 100 billion neurons, that's hard to detect.
- jessriedel 9y agoThe original SlateStarCodex post addresses this. He argues that a microscopic amount of neurogenesis that is too small to be responsible for the effects everyone cares about (depression, brain plasticity, etc.) should be rounded to zero.
- SubiculumCode 9y agoIt is entirely possible that the base-rate of neurogenesis in adult humans is very low, but in response to new stimuli (a new exercise regimen, for example) responds by generating neurons..Perhaps I am missing the information in one of the supplemental pages, but I do not see info on history of exercise or anti-depressant use in the Nature paper.
- deleted 9y ago[deleted]