The synchronization can be avoided somewhat by the use of (also power efficient) asynchronous electronics. You can also employ lower frequency clock them multi

The synchronization can be avoided somewhat by the use of (also power efficient) asynchronous electronics. You can also employ lower frequency clock them multiply it on site. A bit more cost because now you have to handle clock jitter. And then we have computing separated by meters of wire and network fabrics in clusters. So size is not that much of a problem. It is just that free lunch for programmers has ended some 10 years ago.