Well, filtering flaws works much better when you've got a strong prior on what you expect to see. Unfortunately, these priors infect what you think you're seein

Well, filtering flaws works much better when you've got a strong prior on what you expect to see. Unfortunately, these priors infect what you think you're seeing, which is an even bigger problem when you're hoping to see new, novel things never seen before. Here's a nice paper on the problem of overfiltering in electron microscopy. They famously found Einstein by aligning images of white noise: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831464/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831464/