Either there is no way for us to know, thus it is irrelevant and impossible to reason about, or it has perceptible results therefore it is possible (though pote

Either there is no way for us to know, thus it is irrelevant and impossible to reason about, or it has perceptible results therefore it is possible (though potentially not feasible) to "locate" it by followinv casual chain. If it acts in an acausal way, there is still a possibility to "locate" it in terms of e.g. wave equation or other high mathematics. It's also important whether said phenomenon acts locally or not. Former is easier to trace and attribute. Consider a simulation on top of a cluster of machines. Location in such a system may exist and be meaningful and have observable effects. Whether that explanation makes more sense than just "it is so and we don't know why" makes more sense depends on additional pieces of evidence. This is the long answer to "if a tree falls in the forest and there is no one to witness it, does it make a sound".