Or there are multiple factors at play here. For instance, Wyoming has an abnormally high per-capita suicide rate, so it's not hard to find articles that attemp

Or there are multiple factors at play here. For instance, Wyoming has an abnormally high per-capita suicide rate, so it's not hard to find articles that attempt to investigate the reasons for it (e.g. https://fivethirtyeight.com/features/suicide-in-wyoming/ https://fivethirtyeight.com/features/suicide-in-wyoming/). In this case, local culture and the higher rate of per-capita gun ownership is mentioned as likely reasons. You also have the differences in the rate of death by drug overdose in different states (https://www.cdc.gov/drugoverdose/data/statedeaths.html https://www.cdc.gov/drugoverdose/data/statedeaths.html). In a different culture, without access to firearms, people who commit suicide by firearm might otherwise turn to opioids to relieve their pain. Questions like this lead to complicated answers, but fortunately we have access to more data than ever before and, with some effort, a few answers can be teased out for anyone that's curious enough.