If you take the time to research every person on said list and construct an email to them instead of at them, then I don't see the harm. A good baseline test i

If you take the time to research every person on said list and construct an email to them instead of at them, then I don't see the harm. A good baseline test is whether you're working from a template or not — and the answer should be no. Of course, you might have some bits that you paste in that would be repetitive to type, but in general there's a world of difference between composing an email and targeting a campaign. Now, this might be OT but I have noticed that the most successful start-ups are run by an entrepreneur with a very specific unfair advantage: history/experience/connections in the target domain. That's not to say you won't pull it off, but if you have to cold email everyone you hope to sell to, perhaps you should considering partnering with someone that already knows the folks you'd be pitching. It seems obvious, but it's amazing how many folks are arrogant enough to think that they can walk into any vertical and take over.