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> they fail to distinguish between terminal/differentiated cells and tissue stem cells I don’t distinguish them because what I’ve said is true both for differe
by klmr 9y ago
> they fail to distinguish between terminal/differentiated cells and tissue stem cells
I don’t distinguish them because what I’ve said is true both for differentiated and stem cells. I’m not saying that there are no relevant differences between these cells, obviously.
> they imply there is a one-to-one correspondence between the relevant cell divisions and number of total cells at any one time
Uh, where did I imply that? That would obviously be false but, again, it’s not relevant to the argument I’m making.
> The relevant number is divisions since the fertilized egg for each stem cell lineage.
The relevant number for what? I was talking about the total number/size of cells at a given time, not the number of cell divisions, which is an entirely different (but also relevant) facet of tumourigenesis.