3 ms·
Wow interesting, thank you. Bt Delta Endotoxin https://en.wikipedia.org/wiki/Lipopolysaccharide#Health_effects https://en.wikipedia.org/wiki/Lipopolysacchar
by nosuchthing 9y ago
Wow interesting, thank you.
Bt Delta Endotoxin
https://en.wikipedia.org/wiki/Lipopolysaccharide#Health_effects https://en.wikipedia.org/wiki/Lipopolysaccharide#Health_effe...
an interesting side note, endotoxin test have relied on availability of horseshoe crab blood:
The standard assay for detecting presence of endotoxin is
the Limulus Amebocyte Lysate (LAL) assay, utilizing blood
from the Horseshoe crab (Limulus polyphemus).[44] Very low
levels of LPS can cause coagulation of the limulus lysate
due to a powerful amplification through an enzymatic
cascade. However, due to the dwindling population of
horseshoe crabs, and the fact that there are factors that
interfere with the LAL assay, efforts have been made to
develop alternative assays, with the most promising ones
being ELISA tests using a recombinant version of a protein
in the LAL assay, Factor C.[