I might be misinterpreting you, but Opus Magnum is "alchemy"- it makes no attempt to reflect real chemistry, the components are simply abstractions. I can't tel

I might be misinterpreting you, but Opus Magnum is "alchemy"- it makes no attempt to reflect real chemistry, the components are simply abstractions. I can't tell if that would be a pro or a con in your book, but it's a pretty good game.