Apparently artificial sweeteners can stimulate a large insulin response through the sweet taste receptors even though they don't increase the blood sugar - this

Apparently artificial sweeteners can stimulate a large insulin response through the sweet taste receptors even though they don't increase the blood sugar - this over time can cause weight gain and reduce the effectiveness of insulin leading to Type 2 diabetes. I say apparently because its been passed on to me in conversation with friends who medical staff. However that was a number of years ago and I haven't done the research myself to confirm; so as with every thing on the internet, take it with a grain of salt.