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While behavioral genetics is claiming victory in the replication crisis, it should not rest on it's laurels. Replicability is a sign that studies can be conduct
by groceryheist 9y ago
While behavioral genetics is claiming victory in the replication crisis, it should not rest on it's laurels. Replicability is a sign that studies can be conducted consistently. However in the case of behavioral genetics, one fears that all they have managed to do is reproduce and scale up erroneous research designs.
Consider finding 3: "Heritability is caused by many genes of small effect"
This is exactly what you would expect to find if you do a regression with 1000s of variables: many effects, mostly small ones.
Of the 10 findings only 1 is clearly not a fact about statistics in settings where dimensionality is very high relative to sample size.
Finding 5. The heritability of intelligence increases throughout development
Observe that this finding is based not on associations between particular genes and traits, but instead on twin studies. Twin studies have their own problems when it comes to causal identification.
That said, the overall claims here make sense and have some empirical support. My point is that the field has long made outsized claims based on dubious science that is legitimized by it's appropriation of genetics (even though it is a branch of psychology, not biology).
Panofsky's book "Misbehaving Science: Controversy and the Development of Behavior Genetics" is excellent.
- nonbel 9y agoI don't think this paper was even about replication. A replication is when one person/group does something, they write down instructions for someone else to do the same thing, and then the results are compared. Is there a single mention of this happening in that paper? I expected a table of such results. Ie, replication is about doing some very specific thing, instead I see a bunch of vague stuff like "abnormal is normal"...
- amvalo 9y ago> This is exactly what you would expect to find if you do a regression with 1000s of variables: many effects, mostly small ones. No, GWAS is smarter than that.